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Research Program

Department of Anesthesiology – 2006
George C. Kramer, Ph.D., Professor and Director, Resuscitation Research Laboratory

The research performed in the Resuscitation Research Laboratory primarily involves the study of perioperative fluid therapy and their application to the resuscitation of critically injured patients. Specifically, our lab has four funded research projects: 1) Evaluating new blood substitutes for treatment of trauma and hypovolemia using a swine model of hemorrhage. 2) Development and test-ing of novel autonomous and closed-loop resuscitation systems that provide treatment recommendations and autonomous delivery of resuscitation fluids for trauma and burns. Studies are being conducted in animal models and patients. 3) Evaluating novel methods of emergency drug delivery for treating cardiac ar-rest and poisoning using intraosseous vascular access. 4) We are also evaluat-ing treatment of burns and trauma using oral/GI resuscitation of electrolyte solu-tions. This “rediscovered” low-tech approach is applicable to mass casualty and combat casualty care.